Cell Line Lysates
ABclonal Technology TMPRSS6 Rabbit pAb
The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver. Alternative splicing results in multiple transcript variants.
Cayman Chemical IvermectIn B1b 2.5mg
The minor component (<20%) of ivermectin; binds to glutamate-gated chloride channels, inducing irreversible channel opening; ivermectin inhibits replication of SARS-CoV-2 in Vero/hSLAM cells
Abcam Human SLC35C1 knockout HeLa cell lysate.
Human SLC35C1 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PRAP1 knockout HeLa cell lysate.
Human PRAP1 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Biochain Institute Inc Total Protein - Human Adult Normal Tissue: Heart, 1 mg/PK
Tissue total protein is prepared from whole tissue homogenates. It presents a consistent pattern on SDS-PAGE analysis. The total protein is stored in a buffer with protease inhibitor cocktail, and provided at a concentration of 5 mg/ml.
ABclonal Technology CNPase Rabbit pAb
Predicted to enable 2,3-cyclic-nucleotide 3-phosphodiesterase activity. Involved in substantia nigra development. Located in several cellular components, including extracellular space, microtubule, and plasma membrane. Implicated in hypomyelinating leukodystrophy 20, multiple sclerosis, and schizophrenia. Biomarker of alcoholic liver cirrhosis, multiple sclerosis, and restless legs syndrome.
Abcam Human CSF3 knockout K-562 cell lysate.
Human CSF3 knockout K-562 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology TMPRSS6 Rabbit pAb
The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver. Alternative splicing results in multiple transcript variants.
Cayman Chemical N6 4AmInobutyladenosIn5 2.5mg
An aminobutyl derivative of ADP; has been used in the synthesis of quantum dots in ADP-specific TR-FRET assays
ABclonal Technology ATF6 Rabbit pAb
This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis.
Abcam Human IFIT2 knockout A549 cell lysate.
Human IFIT2 knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical GunIn-2-deoxyL-rIbofura 2.5mg
An isomer of dGTP and a telomerase inhibitor (Ki = 15 µM for the human enzyme)
ABclonal Technology EML4 Rabbit pAb
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.
Cayman Chemical ANTIBODY USP8-IN-1 5mg
A USP8 inhibitor (IC50 = 2.6 µM); selective for USP8 over USP7 (IC50 = >20 µM); inhibits colony formation by H1975 cells (IC50 = 30.8 µM)
ABclonal Technology XRCC4 Rabbit pAb
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternate transcript variants such as NM_022406 are unlikely to be expressed in some individuals due to a polymorphism (rs1805377) in the last splice acceptor site.